Wei-Jing Gao, Wei-Cui Li, Chengchu Zeng
Oct 6, 2014
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Influential Citations
99
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Journal
The Journal of organic chemistry
Abstract
An electrochemically promoted coupling of benzoxazoles and amines has been developed, leading directly to the formation of 2-aminobenzoxazoles. The chemistry utilizes catalytic quantities of a tetraalkylammonium halide redox catalyst and is carried out under constant current conditions in a simple undivided cell. The use of excess chemical oxidant or large amounts of supporting electrolyte is avoided. This greatly simplifies the workup and isolation process and leads to a reduction in waste.