R. Shields, M. Nguyen, Ellen G. Press
Jul 1, 2017
Citations
4
Influential Citations
102
Citations
Quality indicators
Journal
Open Forum Infectious Diseases
Abstract
Abstract We used meropenem to successfully treat a patient with bacteremia due to ceftazidime-avibactam-resistant, meropenem- susceptible Klebsiella pneumoniae that carried mutant blaKPC-3. Meropenem was bactericidal against ceftazidime-avibactam- resistant K pneumoniae isolates in vitro. Nevertheless, the role of carbapenems in treating such infections remains uncertain, because meropenem resistance is selected readily during passage experiments.