Narendra R. Chaubey, S. Ghosh
Aug 31, 2012
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Journal
Tetrahedron-asymmetry
Abstract
Abstract The asymmetric desymmetrization of 3-(4-fluorophenyl)glutaric anhydride 9 with lithiated chiral oxazolidin-2-one 8 has been studied. The desymmetrized product was formed with >90% de and converted into known intermediates for both (+)- and (−)-paroxetines.