C. Herdeis, K. Lütsch
1993
Citations
0
Influential Citations
15
Citations
Journal
Tetrahedron-asymmetry
Abstract
Abstract A stereoselective synthesis of the 4 stereoisomers of 2-methyl-4-hydroxy-5-amino-pentanoic acid namely 2R,4S-9a, 2S,4S-9b), ent-9a and ent-b is presented, starting from the known lactones S-1 and R-1 , which are readily available from L- and D-glutamic acid. Only ent-9b shows affinity for GABA B -receptor sites.