S. Yarlagadda, B. Ramesh, C. Ravikumar Reddy
Jan 6, 2017
Citations
0
Influential Citations
31
Citations
Journal
Organic letters
Abstract
An efficient enantioselective α-amination of 2-substituted 3-indolinones has been achieved for the first time using hydroquinidine as a chiral catalyst through an aza-Michael reaction. The desired α-hydrazino esters are obtained in excellent yields with high enantiomeric excess leading to a quaternary stereocenter with a broad substrate scope.