Julen Etxabe, J. Izquierdo, A. Landa
Jun 1, 2015
Citations
0
Influential Citations
32
Citations
Journal
Angewandte Chemie
Abstract
1H-Imidazol-4(5H)-ones are introduced as novel nucleophilic α-amino acid equivalents in asymmetric synthesis. These compounds not only allow highly efficient construction of tetrasubstituted stereogenic centers, but unlike hitherto known templates, provide direct access to N-substituted (alkyl, allyl, aryl) α-amino acid derivatives.