M. Ju, Z. El Rassi
Jan 10, 2000
Citations
0
Influential Citations
4
Citations
Journal
Journal of Liquid Chromatography & Related Technologies
Abstract
Three different glycosidic surfactants, namely cyclohexyl-butyl-β-D-maltoside (CYMAL-4), cyclohexyl-pentyl-β-D-maltoside (CYMAL-5), and cyclohexyl-hexyl-β-D-maltoside (CYMAL-6), were compared in the enantioseparation of some dansyl amino acids and methylated tryptophans. The three CYMAL surfactants have the same chiral maltoside head group but differ in the length of the hydrophobic tail. Increasing the length of the hydrophobic tail seems to shift the optimum surfactant concentration for maximum enantioresolution towards lower concentration values. In order to extend the range of optimum surfactant concentration over which maximum enantioresolution can be achieved, mixed CYMAL surfactant systems were introduced and evaluated. They consisted of mixing CYMAL-6 with either cyclohexyl-methyl-β-D-maltoside (CYMAL-1) or cyclohexyl-ethyl-β-D-maltoside (CYMAL-2).