D. E. Justice, J. Malpass
Jun 26, 1995
Citations
0
Influential Citations
8
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Novel endo - 6,7-epoxy-8-azabicyclo[3.2.1]octane derivatives and the corresponding exo -analogues have been synthesized and show substantially different reactivity; the resistance of the exo -epoxides to ring opening during hydride reduction and catalytic hydrogenolysis is exploited in a total synthesis of scopine, pseudoscopine, and nor -derivatives.