Masafumi Ueda, S. Kawai, Masataka Hayashi
Jan 11, 2010
Citations
1
Influential Citations
49
Citations
Journal
The Journal of organic chemistry
Abstract
A new efficient synthesis of 2-substituted tetrahydroquinolines has been achieved by the domino reaction of N-indanyl(methoxy)amines, which consists of three types of reactions: elimination of an alcohol, the rearrangement of an aryl group, and the addition of an organolithium or magnesium reagent. The synthetic utility of this approach is demonstrated by the stereoselective formal synthesis of (+/-)- martinellic acid.