U. Desai, M. A. Kulkarni, Kapil S. Pandit
Jun 17, 2014
Citations
0
Influential Citations
19
Citations
Journal
Green Chemistry Letters and Reviews
Abstract
A simple, economical, and environmentally benign protocol has been described for one-pot synthesis of medicinally privileged 2-amino-3,5-dicarbonitrile-6-sulfanylpyridines by three-component condensation between aldehyde, malononitrile, and thiol using diethylamine as a catalyst. Ambient temperature and avoidance of conventional work-up as well as purification procedure qualify this cost-effective protocol for “green synthesis.”