M. Dukat, R. Glennon
Jun 1, 2003
Citations
1
Influential Citations
23
Citations
Journal
Cellular and Molecular Neurobiology
Abstract
Epibatidine is a natural product that was isolated and identified by Daly and coworkers in 1992. Since that time, it has had a profound influence on the investigation of α 4β 2 nicotinic cholinergic (nACh) receptor pharmacophore models, and has inspired the development of novel agents with therapeutic potential in CNS disorders. Apart from acetylcholine and nicotine, probably no other agent has had as much recent impact on nACh research as has epibatidine.