M. Alaiz, J. Girón, F. Hidalgo
1989
Citations
0
Influential Citations
14
Citations
Journal
Synthesis
Abstract
A method to protect the amino group of the amino acids using diethyl (ethoxymethylene) malonate is described. The resulting derivatives are easily esterified with different alkylation agents. Elimination of the N-protecting group with bromine in chloroform affords the hydrobromides of the amino acid esters