F. Qing, Yanmei Zhang
Sep 22, 1997
Citations
0
Influential Citations
16
Citations
Journal
Tetrahedron Letters
Abstract
Ethyl 3-iodo-4,4,4-trifluoro-2(Z)-butenoate (2) was regio- and stereo-specific prepared from ethyl 4,4,4-trifluoro-2-butynote (1). The Sonogashira reaction of 2 with terminal alkynes afforded the (2Z)-en-4-ynoic acid derivatives containing trifluoromethyl group (4). © 1997 Elsevier Science Ltd.