H. J. Jakobsen, P. Madsen, S. Lawesson
1966
Citations
0
Influential Citations
6
Citations
Journal
Tetrahedron
Abstract
Abstract Ethyl isopropylcyanoacetate and ethyl mono-trideuteromethyl-isopropylcyanoacetate have been prepared by reaction of ethyl ethylidenecyanoacetate with methylmagnesium iodide and trideuteromethylmagnesium iodide, respectively. The doubling of the methyl doublet in the NMR spectra of these two compounds shows that the methyl groups of the former compound are magnetic non-equivalent and that the latter compound is obtained as both the erythro and threo diastereomer.