S. A. Soffar, D. M. Metwali, S. Abdel-Aziz
Dec 1, 2001
Citations
2
Influential Citations
42
Citations
Quality indicators
Journal
Journal of the Egyptian Society of Parasitology
Abstract
Berberine is a quaternary alkaloid derived from the plant Berberis aristata having antibacterial, antiamoebic, antifungal, antihelminthic, leishmanicidal and tuberculostatic properties. The effect of berberine sulphate salt on the growth of Trichomonas vaginalis in vitro was compared to the efficacy of metronidazole as a reference drug. Results showed that berberine sulphate was comparable to metronidazole as regards potency with the advantage of being more safe and possible replacement in metronidazole resistant cases.