G. D'elia, S. Borg, L. Hermann
Jan 1, 1977
Citations
0
Influential Citations
16
Citations
Quality indicators
Journal
Acta Psychiatrica Scandinavica
Abstract
Lofepramine, an imipramine analogue, was compared with imipramine in a multicentre, double‐blind clinical trial. The 62 patients (31 in each of two treatment groups) had a depressive syndrome that normally would have been treated with a tricyclic antidepressant. These patients had not received any adequate treatment for their present depressive episode. After a wash‐out period and once a week during treatment (up to 5 weeks), routine laboratory tests and electrocardiograms were done. The dosage was 50 mg t.i.d. for imipramine and 70 mg t.i.d. for lofepramine.