Shlomo Cohen, A. Zoran, Y. Sasson
Dec 24, 1998
Citations
0
Influential Citations
9
Citations
Journal
Tetrahedron Letters
Abstract
Abstract The Hoffman degradation reaction is proposed as an unequivocal proof for the validity of the extraction mechanism in Phase Transfer Catalysis (PTC) in the presence of solid NaOH. 4-Chlorobutyronitrile is found to yield cyclopropyl cyanide via an extraction route while 4-bromobutyronitrile reacts to form the same product by the prevalent interfacial mechanism.