T. Le, N. T. T. Chau, Tai T. Nguyen
Jan 21, 2011
Citations
0
Influential Citations
11
Citations
Journal
The Journal of organic chemistry
Abstract
The metalation of 4-hydroxy-6,7-dimethoxy-8-methyl-2-naphthoic acid (8) affording trianion 6 is presented and applied to the regioselective efficient construction of a series of 5,5'-didesisopropyl-5,5'-dialkylapogossypol derivatives 3 that are potent pan-active inhibitors of antiapoptotic Bcl-2 family proteins.