I. Knox, J. Ennever, W. Speck
Feb 1, 1985
Citations
1
Influential Citations
24
Citations
Quality indicators
Journal
Pediatric Research
Abstract
ABSTRACT: Lumirubin, a water-soluble photoproduct of bilirubin formed in vivo during phototherapy, is excreted in the urine. In premature infants with little or no bilirubin conjugating activity, lumirubin is the principal yellow pigment found in the urine during phototherapy. The clearance rate of lumirubin in nine premature infants varied from 0.05 to 0.65 ml/min and increased with postconceptional age in parallel with increased creatinine clearance rate. The amount of lumirubin excreted per 24 h was estimated to be from 0.2 to 9.4 mg with a mean of 3.2 mg. The urinary excretion of lumirubin is a significant pathway for pigment elimination during phototherapy.