R. Page, R. Heffner, Andrew Frey
1941
Citations
2
Influential Citations
30
Citations
Quality indicators
Journal
Digestive Diseases and Sciences
Abstract
1. Urinary silica excretion studies were carried out on five healthy, male subjects on regular diets and the mean twenty-four-hour excretion was found to be 16.2 mg. of silica. 2. The urinary excretion of silica varied widely and was proportional to the amount of silica in the diet. 3. Urinary silica excretion was increased in healthy subjects when magnesium trisilicate was taken by mouth. 4. These studies suggest that silica, is excreted by the kidneys in direct proportion to the amount absorbed and that there is probably no definite renal threshold for silica. 5. No evidence has been found that the administration of magnesium trisilicate by mouth has any deleterious effect on the human or animal organism.