H. Bösch, Sergio Cesco‐Cancian, L. R. Hecker
2001
Citations
0
Influential Citations
4
Citations
Journal
Organic Process Research & Development
Abstract
Preparation of methyl (S)-3-amino-3-(3‘-pyridyl)propionate dihydrochloride in high enantiomeric purity by selective crystallization of a diastereomeric salt of a carboxylic acid precursor (N-BOC-protected) with (1R,2S)-(−)-ephedrine is described. Further demonstration of the usefulness of this procedure to resolve other 3-amino-3-[(substituted)pyridyl]propionic acids is also described.