Riccardo Mossetti, D. Saggiorato, G. Tron
Nov 18, 2011
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0
Influential Citations
20
Citations
Journal
The Journal of organic chemistry
Abstract
We describe a simple and novel protocol for the synthesis of tetrahydro-1,4-benzodiazepin-2-ones with three points of diversity, exploiting the acylating properties of the recently rediscovered Ugi-imide. The final compounds can be easily prepared in three synthetic steps using a multicomponent reaction, a Staudinger reduction, and an acylative protocol, with good to excellent yields for each synthetic step.