M. Friedrich, A. Wächtler, A. Meijere
Mar 1, 2002
Citations
0
Influential Citations
14
Citations
Journal
Synlett
Abstract
2-(Acylmethylene)propanediol diacetates, which cyclize readily under acidic conditions to give furans (76-84%) react with primary amines under palladium catalysis to give 1,2,4-trisubstituted pyrroles in moderate to good yields (39-53%). When glycine methyl ester is used as the amine, substituted methyl pyrrol-1-ylacetates (31-82%) are obtained.