K. Dawood, N. A. Kheder, E. Ragab
Jan 29, 2010
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Influential Citations
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Phosphorus, Sulfur, and Silicon and the Related Elements
Abstract
3-Bromoacetyl-1,5-diphenyl-1H-pyrazole-4-carbonitrile (1) reacts with sodium benzenesulfinate to give the corresponding ketosulfone 2. Treatment of 2 with hydrazonoyl chlorides 3a,b gives the 3,3′-bipyrazoles 5a,b. Ketosulfone 2 reacts also with arylidenemalononitriles to give the pyrazolylpyridones 10a,b. The reaction of compound 2 with phenylisothiocyanate and potassium hydroxide and treating intermediate with hydrazonoyl halides and with α-haloketones gives the 1,3,4-thiadiazoles 18a–c and thiophenes 21a–f, respectively.