K. Yamashita, Michihiro Tsuboi, M. Asano
Jan 15, 2012
Citations
1
Influential Citations
19
Citations
Journal
Synthetic Communications
Abstract
Abstract In this communication, we report the superior role of 1,3-dimethyl-2-imidazolidinone (DMI) as a solvent for aromatic Finkelstein iodination (AFI), the conversion of aryl bromides to aryl iodides. DMI accelerates the reaction rate and affords product(s) that could not be prepared using previous methods. Our findings for AFI avoid the use of toxic solvents such as N,N-dimethylformamide and hexamethylphosphoramide. GRAPHICAL ABSTRACT