Wenlin Xie, Ying Zhou, Chuangping Xiao
Feb 1, 2012
Citations
0
Influential Citations
4
Citations
Journal
Journal of Chemical Research
Abstract
A simple and efficient method for the iodination of 5,6-di(arylamino)pyridine-2,3-diones using iodine with ethanol at room temperature is described. Notable advantages include mild reaction condition, no need for a catalyst, short reaction time, simple practical procedure, giving excellent yield of the product. Iodopyridines have important medical applications as drug or diagnostic aids and radiolabelled compounds.