V. Sudhir, R. Baig, S. Chandrasekaran
May 1, 2008
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0
Influential Citations
24
Citations
Journal
European Journal of Organic Chemistry
Abstract
A practical and high-yielding regioselective synthesis ofseveral enantiopure 4,5,6,7-tetrahydro[1,2,3]triazolo[1,5-a]pyrazin-6-ones is described starting from primary amines and α-amino acid derivatives in a three-step reaction sequence by employing a constrained intramolecular “click” reaction as the key step. The method obviates chromatographic purification of products.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)