G. Brahmachari, B. Banerjee
Oct 30, 2014
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0
Influential Citations
66
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Journal
ACS Sustainable Chemistry & Engineering
Abstract
A simple, straightforward, and highly efficient pseudo-three-component one-pot synthesis of a series of pharmaceutically interesting functionalized 3,3-bis(indol-3-yl)indolin-2-ones (3a–3w) and 2,2-bis(indol-3-yl)acenaphthylen-1(2H)-one derivatives (5a–5d) has been developed based on a low-cost and environmentally benign commercially available sulfamic acid as an organo-catalyst in aqueous ethanol at room temperature. The salient features of the present protocol are mild reaction conditions, excellent yields, high atom-economy, eco-friendliness, easy isolation of products, no column chromatographic separation, and reusability of reaction media.