U. Girreser, D. Heber, Martin Schuett
May 1, 1998
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0
Influential Citations
11
Citations
Journal
Synthesis
Abstract
: A generally applicable synthesis of 1-aryl-2-(dimethyl-aminomethyl)prop-2-en-1-ones 2 involving reaction of aromatic methyl ketones 1 with paraformaldehyde and dimethylamine in dimethylformamide is described. The majority of experiments were conducted with these reagents, but the process can also be performed using dimethyl(methylene)ammonium chloride.