M. M. Mojtahedi, L. Pourabdi, M. S. Abaee
Mar 31, 2016
Citations
0
Influential Citations
21
Citations
Journal
Tetrahedron
Abstract
Abstract 1-Methylpiperidin-4-one and its sulfur and oxygen analogues undergo individual facile pseudo four-component reactions with two folds of malononitrile and various aldehydes by using ultrasonic irradiation and deficient quantities of pyrrolidine. As a consequence, ortho-aminocarbonitrile products are formed efficiently in the mixture within 1–2 min of irradiation. Alternatively, the same mixtures of the reactants would lead to direct high-yield formation of dicyanoanilines, a group of products which are also attainable in a stepwise manner starting from the respective ortho-aminocarbonitriles.