Matthew T. Tudge, H. Mashima, C. Savarin
Feb 4, 2008
Citations
0
Influential Citations
13
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Borane–dimethoxyethane generated from sodium borohydride–bromine mixtures efficiently reduces a wide range of malonate derivatives to the corresponding 1,3-diols. This new reagent system represents a milder alternative to current methods available, providing the requisite 1,3-diols in higher yields over shorter reaction times.