Q. Zeng, Bangzhou Huang, K. Danielsen
Oct 16, 2004
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Influential Citations
10
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Journal
Organic Process Research & Development
Abstract
A facile and industrially viable process for preparation of 2,6-dichloropurine is reported. The process involves direct chlorination of xanthine with phosphorus oxychloride and a weak nucleophilic organic base, such as amidine, guanidine base, or Proton-Sponge.