Frédéric C. Bargiggia, W. Murray
May 8, 2006
Citations
0
Influential Citations
9
Citations
Journal
Tetrahedron Letters
Abstract
A versatile synthesis of α and α′ disubstituted N-hydroxypiperidine and N-hydroxypyrrolidine by consecutive double 1,4-addition of hydroxylamine on the corresponding bis α,β-unsaturated diester is described. This reaction takes place an environmentally friendly (ethanol/water) system and at room temperature.