M. Raslan, M. Ichalil, S. Sayed
1999
Citations
0
Influential Citations
4
Citations
Journal
Heterocyclic Communications
Abstract
2-cyanomethy Ibenzothiazole 1 reacts with acetone derivatives 2a-d. or acetonitrile derivative 6a-d in the presence of sulfiur and triethvlamine afforded the novel polysubstituted thiophene. Treatment of I with alkylidenemalononitnle derivatives lla-h resulted in the formation of benzo[g]thiazo[3.2-a]pyridines in high yield. Introduction: Benzothiazole derivatives have attracted a great deal of interest due to their biological and commerical importance. They have been found to have their antiviral 1): antibacterial(2) and fungicidal! 3) activites. They are also useful as anti-allergic(4). an theliminic(5) agent and histamine H2 antagomsts(6) and appetite depressants! 7). intermediates for dyes(8) and photographic