Y. Gong, Katsuya Kato
Mar 1, 2002
Citations
0
Influential Citations
11
Citations
Journal
Synlett
Abstract
Several ortho- and para-(1-chloro-2,2,2-trifluoroethyl)phenols were prepared from the corresponding alcohols and thionyl chloride in the presence of pyridine. They reacted smoothly with sodium borohydride and Grignard reagents under mild conditions, forming 2,2,2-trifluoroethyl- or 1-trifluoromethylalkylphenols in high yields.