M. Chizhova, O. Bakulina, A. Ivanov
Sep 9, 2015
Citations
0
Influential Citations
9
Citations
Journal
Tetrahedron
Abstract
Abstract A new facile synthesis of pyrido[2,3-d]pyrimidin-4-ones via cyclocondensation of 4,6-dichloro-2-methylsulfanylpyrimidine-5-carbaldehyde with β-alkyl and β-aryl-β-aminoacrylic esters followed by hydrolysis of chlorine atom at position 4 of pyridopyrimidine ring has been developed. The cyclocondensation was found to be accelerated by acid.