E. Mawer, C. Taylor, J. Backhouse
Mar 24, 1973
Citations
0
Influential Citations
199
Citations
Quality indicators
Journal
Lancet
Abstract
Abstract 1,25-dihydroxycholecalciferol (1,25- D.H.C.C.) could not be detected in the serum of patients with chronic renal insufficiency after injection of radioactive cholecalciferol. These patients were comparable in degree of vitamin-D deficiency with controls who formed 1,25-D.H.C.C. It is suggested that inability to form this active metabolite of vitamin D contributes to the vitamin-D-resistant osteomalacia of chronic renal insufficiency.