M. N. Reddy, Pittala Praveen Kumar, E. Rajanarendar
Jan 2, 2017
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0
Influential Citations
11
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Journal
Green Chemistry Letters and Reviews
Abstract
ABSTRACT A facile and convenient procedure for the synthesis of isoxazolyl pyrido[2,3-b][1,4]oxazin-2(3H)-ones via Smiles rearrangement from isoxazole amine, chloroacetyl chloride and 2-chloro-3-hydroxypyridine using [HMIm]BF4 as task-specific ionic liquid has been described. The protocol proves to be efficient and environmentally benign in terms of high yields, eco-friendly solvent, ease of recovery, and reusability of reaction medium. GRAPHICAL ABSTRACT