G. Landoni, D. Poli, T. Bové
Jan 1, 2007
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Influential Citations
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Journal
Clinical Research in Cardiology Supplements
Abstract
Fenoldopam mesylate is a useful antihypertensive and diuretic drug. In this review, we examine the evidence based medicine wheter to use fenoldopam in cardiac surgery patients and/or in critically ill patients with or at risk for acute renal failure (ARF). We conclude that from published studies it seems that fenoldopam could be beneficial if a prolonged infusion is performed starting early in the process of ARF in critically ill patients. Unfortunately there is still virtually no definitive evidence of efficacy, especially in cardiac surgery patients. A large, multicenter, randomized, controlled trial (RCT) is needed to confirm the promising but conflicting findings of this drug.