A. Bogdanov, T. A. Kutuzova, Vladimir F. Mironov
Mar 1, 2016
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0
Influential Citations
16
Citations
Journal
Russian Journal of General Chemistry
Abstract
Hydrazones are important and interesting class of organic nitrogen compounds exhibiting a broad spectrum of biological activity like antimicrobial [1], antiinflammatory [2], antitumor [3], etc. Among these versatile compounds isatin-based hydrazones are worthy of notice due to a number of useful properties. These derivatives are interesting as plasticizers and antioxidants [4], various enzyme inhibitors [5, 6] and complexing agents [7, 8]. Furthermore, there are data on high antimicrobial activity of some isatin-3acylhydrazones [9, 10]. However, one factor which does not allow performance of a more extensive research in this field is the low solubility of the target compounds in the water.