Vaibhav P Mehta, Anuj S. Sharma, E. V. Van der Eycken
Feb 20, 2008
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0
Influential Citations
56
Citations
Journal
Organic letters
Abstract
An unprecedented desulfitative Sonogashira-type cross-coupling protocol is exemplified by the synthesis of substituted 5-chloro-3-alkynylpyrazinones from the corresponding 5-chloro-3-(phenylsulfanyl) pyrazin-2(1H)-ones. The applicability of the method is extended to solid-phase linked pyrazin-2(1H)-ones as well as to some oxazinones, pyrazines, and phenyl thioesters.