M. Sollogoub, K. Fox, Vicki E. C. Powers
Apr 22, 2002
Citations
1
Influential Citations
26
Citations
Journal
Tetrahedron Letters
Abstract
The synthesis of 1-deazacytidine, the C-nucleoside analogue of cytidine, is described. It involves coupling of a protected 2-amino-5-bromopyridine with perbenzylated ribonolactone and transformation of the pyridine ring into the desired substituted pyridone. This synthesis completes the family of C-nucleosidic analogues of natural nucleosides.