Y. Aoyagi, Y. Adachi, Shunta Akagi
Apr 1, 2009
Citations
0
Influential Citations
2
Citations
Journal
Bioorganic & medicinal chemistry letters
Abstract
A potent antiinflammatory methyl picolinate alkaloid CJ-14877 [(+)-1] and its enantiomer (-)-1 were synthesized in two steps starting from commercially available methyl 5-bromopicolinate. The synthesis includes microwave-assisted Suzuki coupling reaction and Sharpless asymmetric dihydroxylation.