Wen-Sen Li, J. Thottathil, M. Murphy
Sep 5, 1994
Citations
0
Influential Citations
7
Citations
Journal
Tetrahedron Letters
Abstract
We have found that in the presence of fluoride ion, nitrotoluenes of type 1 undergo Michael addition to activated α, β-unsaturated esters of type 2 in good to excellent yield (Scheme 1). The generality and limitation of this reaction and its application to the chiral synthesis of benzazepine 4 are described.