J. Marecek, G. Prestwich
1989
Citations
0
Influential Citations
26
Citations
Journal
Tetrahedron Letters
Abstract
Abstract 2-Fluoro-2-deoxy-Ins(1,4,5)P 3 ( ) and 2,2-difluoro-2-deoxy-Ins(1,4,5)P 3 ( ) were synthesized from protected inositol precursors. The monofluoro compound with free 3,6-hydroxyl groups underwent slow defluorination at pH > 13, as determined by 19 F-NMR, while the difluoro compound was inert.