G. Lal
May 1, 1993
Citations
0
Influential Citations
197
Citations
Quality indicators
Journal
Journal of Organic Chemistry
Abstract
The new «N-F»-type electrophilic reagent family of 1-alkyl-4-fluoro-1,4-diazabicyclo[2.2.2]octane salts 8d (derived from elemental fluorine (F 2 ) and 1-alkyl-1,4-diazabicyclo[2.2.2]octane salts) has been found to be very effective for the fluorination of a wide variety of organic substrates. These include steroidal enol acetates and silyl enol ethers, phenyl-substituted olefins, sulfides bearing α-H atoms, certain carbanions, and mildly activated aromatic compounds. The products were obtained with good yields and regioselectivity under very mild reaction conditions