R. Pews, J. Gall
May 1, 1991
Citations
0
Influential Citations
5
Citations
Journal
Journal of Fluorine Chemistry
Abstract
Abstract The preparation of 2,6-difluoroaniline from 1,3,5-trichlorobenzene is described. 1-Chloro-3,5-difluorobenzene prepared via KF exchange on 1,3,5-trichlorobenzene is dichlorinated and nitrated in a single reactor to a mixture of trichlorodifluoronitrobenzenes. The latter are reduced to ∼4:1 isomeric mixture of 2,6-difluoroaniline and 2,4-difluoroaniline.