R. Chambers, J. Hutchinson
Oct 1, 1998
Citations
1
Influential Citations
45
Citations
Journal
Journal of Fluorine Chemistry
Abstract
Abstract Catalysis of the reaction between fluorine and a range of 2-substituted carbonyl compounds has been investigated. Most notably, the preparation of diethyl-2-fluoromalonate has been achieved in high yield by fluorination of diethylmalonate in the presence of hydrated copper nitrate. Reactions between fluorine and carbanions derived from 2-substituted carbonyl compounds, including phosphonates, sulphones and nitriles, are also discussed.