Alexander S. Konev, Sara Stas, Mikhail S. Novikov
2008
Citations
0
Influential Citations
11
Citations
Journal
Tetrahedron
Abstract
Abstract Reaction of 2-fluoroaziridines with potassium alkynyltrifluoroborates in the presence of BF3·OEt2 leads to fluorinated propargyl amines in moderate to good yields. The reaction proceeds as an in situ isomerization of 2-fluoroaziridines to α-fluorinated imines, followed by the reaction of the imine with alkynyldifluoroborane, which is generated in situ from the potassium alkynyltrifluoroborates and BF3·OEt2.