J. Ruzicka, M. T. Baker
Mar 1, 1995
Citations
0
Influential Citations
5
Citations
Journal
Journal of Fluorine Chemistry
Abstract
Abstract The degradation of the experimental anesthetic, fluoro-dideutero-methyl 1,1,1,3,3,3-hexafluoroisopropyl ether (D 2 -sevoflurane) on soda lime (Sodasorb ® ) has been compared with sevoflurane and examined in regard to product deuterium content. Similar products and rates of degradation were found between sevoflurane and D 2 -sevoflurane, and all D 2 -sevolfurane products contained the fluorodideuteromethoxy group. Four products contained a trideuteromethoxy moiety, indicating the addition of methanol derived from the fluoromethoxy carbon of D 2 -sevoflurane.